I tried it and did the following test: With 2 otherwise identical rigs trolled side-by-side with clear line in a clear lake, the clear line outfished Cajun 5 to 1. The fish were about 15 feet down that day and could obviously see the red line.
That was all I needed to know. Back to Stren and Trilene Sensation for me.
In a murky lake it probably doesn't matter (a buddy of mine uses it for leaders and catches tons of walleyes).